In a new study, scientists have found three previously-available drugs that may be effective at treating COVID-19 in its early stages.
The research, which appears in the journal ACS Pharmacology & Translational Science, is valuable in helping researchers identify treatment candidates for clinical trials.
SARS-CoV-2 and its associated disease, COVID-19, have had a profoundly negative effect on global economies, culture, people’s everyday lives, and above all, on people’s health.
To date, there have been more than 1,150,000 recorded deaths from the disease. There is also mounting anecdotal evidence of the long-term negative health effects it can have on people who recover from the initial illness.
Due to COVID-19’s lethality, and the fact that the disease is highly contagious, scientists are rushing to develop a vaccine. However, producing vaccines that are also safe and effective takes a considerable amount of time.
According to a report in The Lancet, on average, vaccines take 10 years to develop. Even with experts greatly accelerating research due to the urgency of the global pandemic, the report notes that an initial vaccine may take more than 18 months to be developed, manufactured, and distributed to people around the world.
Consequently, scientists have been researching vaccines and potential treatments that may ultimately reduce the chance of a person dying if they develop the disease.
This typically involves repurposing previously available drugs that may also be effective in treating COVID-19. This is important as, much like developing a working vaccine, finding new drugs that can treat COVID-19 may take a long time.
To date, the only repurposed drug that has shown signs of being effective is remdesivir, originally developed to treat Ebola in 2014.
As a consequence, identifying effective drugs that experts can repurpose to treat COVID-19 is particularly pressing.